Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH
Published in Nature Biotechnology, 2023
CV
Education
- PhD. in the lab of Sten Linnarsson, Karolinska Institute, 2018 - now
- MSc. in Biomedical Sciences, Molecular Neuroscience specialization, University of Amsterdam, 2018 (Judicium Cum Laude)
- BSc. in Psychobiology, University of Amsterdam, 2016 (with Honours)
- BSc. in Biomedical Sciences, University of Amsterdam, 2016
Interests
- Epigenetics
- Developmental Biology
- Neuroscience
- Bioinformatics
- Statistical Modeling
- Technology development
- Python programming
Publications
Dynamics of chromatin accessibility during human first-trimester neurodevelopment
Published in Nature, 2024
Talks
10X Genomics webinar about applying single cell ATAC-seq in the developing human brain
Talk at 10Xgenomcis webinar, Online
Teaching
Student projects
- Unravelling RNA regulation using single molecule fluorescence hybridization
- 2017-2018: Karolinska Institute, Sten Linnarsson group
- Languages: Python
- duties: method development of novel high throughput smFISH method and analysis of smFISH data
- Supervisor: Simone Codeluppi
- Integrative Genome-Wide analysis for the detection of molecular drug targets in late onset Alzheimer’s disease
- 2017: VU Uuniversity Amsterdam, Danielle Posthuma group
- Languages: R, MATLAB
- duties: collection, integration and analysis of scRNA-seq data, GWAS summary statistics and protein-protein interaction data
- Supervisor: Erdogan Taskesen
- DOT1, AF9 and H3K79 methylation in the Cortex
- 2015: University of Amsterdam, Marten Smidt group
- duties: using molecular biology techniques like western blot, immunohistochemistry and PCR to characterize the effects of AF9 knock-out in the mouse cortex.
- Supervisor: Hendrikus van Heesbeen